Gene regulation in immune cells refers to the mechanisms used by immune cells to increase or decrease the production of specific gene products. Here, Fry and colleagues examine the impact of ...

How does a gene, which consists of a string of DNA hidden in a cell's nucleus, know when it should express itself? How does this gene cause the production of a string of amino acids called a protein?

They seek to understand how cells modulate gene expression by modulating chromatin and DNA organization. Fred Hutch researchers have done pioneering work in the areas of gene regulation, chromatin ...

Researchers hope the AI tool will aid in the development of cell-specific gene therapies to treat diseases such as cancer.

Each cell contains over 6-billion DNA letters ... Histones also play key roles in gene regulation. Small chemical modifications can be added to histones, which allow proteins to access the ...

This important study of regulatory elements and gene expression in the craniofacial region of the fat-tailed dunnart shows that, compared to placental mammals, marsupial craniofacial tissue develops ...

Usher syndrome (USH) is a rare hereditary genetic disorder characterized by hearing loss, visual impairment, and balance dysfunction. Patients with USH have ...

The course explores gene regulation in eukaryotes from nuclear organisation to cytosolic control, with a focus on animals and humans. The molecular mechanisms of transcription within a chromatin ...

Nearly all cells in the human body contain the same ... Despite its importance, understanding gene regulation has been very challenging because previous methods to study regulatory proteins ...

Understanding the structure, function, and regulation of genes is crucial for advancing our knowledge of biology and developing new strategies for diagnosing, treating, and preventing genetic ...

Molecular biologists decode the epigenetic silencing of problematic retroviral gene sequences. LMU molecular biologist Gunnar Schotta decodes the epigenetic silencing of problematic retroviral gene ...

Breast cancer cells exhibit organotropism during metastasis, showing preferential homing to certain organs such as bone, lung, liver, and brain. One potential explanation for this organotropic ...