How do bacteria ... changes in gene expression. In the case of the trp operon, the ligand tryptophan is required for the repressor to work (repressible negative regulation). But other operons ...

How would you make transcription and translation work when you no longer have a nucleus? Bacteria have an interesting answer. Attenuation, or dampening, of the trp operon is made possible by the ...

The second project focuses on mechanisms of gene regulation in bacteria, particularly Escherichia coli, that involve reiterative transcription and/or transcription start site switching. Reiterative ...

1. Design principles and biotech applications of a eukaryote-like CRISPR-enabled gene activation tool in bacteria. 2. Summarize principles and RNA sensing applications of reprogramming tracrRNAs in ...