In other words, these regulatory mechanisms control gene expression ... Nonetheless, each of these strategies begins at the level of DNA. Eukaryotic cells contain a large amount of DNA, and ...

Optogenetic methods have so far been based almost exclusively on activating the transcription of DNA ... target gene can be ...

EMBL researchers showed for the first time that adding a sugar to proteins inside cells is crucial for embryo development and for shutting down ...

Our research in this area includes uncovering fundamental mechanisms that regulate how genes are turned on and off in normal cells and how the misregulation of these mechanisms can lead to cancer, as ...

Researchers hope the AI tool will aid in the development of cell-specific gene therapies to treat diseases such as cancer.

7 “There's chromatin looping, which is the idea that you can have [DNA] folding in three-dimensional space. [This refers to] gene regulation that's dictated ... different genes must be tuned to normal ...

Penn researchers introduce mvGPT, a gene editing tool that edits DNA, activates genes and represses gene expression ...

DNA’s iconic double helix has long been the symbol of life’s blueprint. However, the human genome conceals far more ...

A new technology, mvGPT, is capable of precisely editing genes, activating gene expression, and repressing genes all at the same time.

Researchers analyze various aspects of gene regulation, among which are the three-dimensional structure of the genome and DNA methylation, which differ for different cell types and play significant ...

The course explores gene regulation in eukaryotes from nuclear organisation to cytosolic control, with a focus on animals and humans. The molecular mechanisms of transcription within a chromatin ...