They seek to understand how cells modulate gene expression by modulating chromatin and DNA organization. Fred Hutch researchers have done pioneering work in the areas of gene regulation, chromatin ...
In other words, these regulatory mechanisms control gene expression ... Nonetheless, each of these strategies begins at the level of DNA. Eukaryotic cells contain a large amount of DNA, and ...
As trp levels increase ... changes in gene expression. In the case of the trp operon, the ligand tryptophan is required for the repressor to work (repressible negative regulation).
7 “There's chromatin looping, which is the idea that you can have [DNA] folding in three-dimensional space. [This refers to] gene regulation that's dictated by very long-range contacts ... in which ...
The course explores gene regulation in eukaryotes from nuclear organisation to cytosolic control, with a focus on animals and humans. The molecular mechanisms of transcription within a chromatin ...
Researchers analyze various aspects of gene regulation, among which are the three-dimensional structure of the genome and DNA methylation, which differ for different cell types and play significant ...
DNA can be cut up and separated, which can form a 'bar code' that is different from one person to the next. A gene is a small section of DNA in a chromosome. Each gene codes for a particular ...