Researchers have developed an AI model that accurately predicts gene activity in any human cell, providing insights into ...

Using a new artificial intelligence method, researchers at Columbia University Vagelos College of Physicians and Surgeons can ...

Scientists have long studied the processes that underlie gene expression and the ... specialized cells from stem cells, and aid cells in remembering their own identity and function.

The discovery that different nutrients can change a cell's gene expression, function, and identity significantly advances scientists' understanding of the relationship between nutrition and ...

The immune system relies on specialized “effector” T cells to fight off pathogens. However, in chronic infections such as cancer or HIV, the perpetual activation of these cells can turn them ...

Our research in this area includes uncovering fundamental mechanisms that regulate how genes are turned on and off in normal cells and how the misregulation of these mechanisms can lead to cancer, as ...

"By uncovering how transcription factors interact with chromatin architecture, we can better understand gene regulation and cellular identity ... gene expression, directing cells to differentiate ...

The discovery that different nutrients can change a cell's gene expression, function, and identity significantly advances scientists' understanding of the relationship between nutrition and ...

Using a new artificial intelligence method, researchers at Columbia University Vagelos College of Physicians and Surgeons ...

This finding highlights how metabolic changes influence T cell identity and opens avenues for interventions to sustain immune function. The discovery that different nutrients can change a cell’s gene ...

The authors demonstrated cellular heterogeneity of companion cells (CCs) and also suggested the CC subpopulation that highly expressed the florigen gene FT. Based on this finding, they further ...