The death, which investigators linked to a preparatory chemo treatment rather than Beam's medicine, highlights the risks of using decades-old transplant drugs alongside cutting-edge CRISPR medicines.
This oral medication is considered a first-line treatment for sickle cell disease, and can help reduce pain crises. Hydroxyurea causes the body to produce fetal hemoglobin, a type of hemoglobin ...
The therapy led to higher levels of fetal hemoglobin and lower levels of sickle-shaped cells. Beam also said signs of red blood cell destruction had normalized for all four patients and there were ...