Ribosomes are complexes of rRNA molecules and proteins, and they can be observed in electron micrographs of cells. Sometimes, ribosomes are visible as clusters, called polyribosomes. In eukaryotes ...
Electron microscopy uses a beam of electrons to illuminate ... disease — we visualized the context-dependent action of the ribosome-targeting antibiotic chloramphenicol simultaneously at atomic ...
Peter Shen, a postdoctoral researcher in Frost’s lab, isolated RQCs from yeast cells and used cryo-electron microscopy to develop three-dimensional images of their interactions with large ribosomal ...
This important study by Bi and colleagues employed a clever genetics screen to uncover the role of the GidB rRNA methylase in translation fidelity, under certain conditions, in Mycobacterium smegmatis ...
An international research collaboration has shed new light on the molecular basis of gene expression, the fundamental biological process that underpins how all organisms use their genetic information.
"Understanding how the ribosome captures or 'recruits' the ... We saw them in action using cryo-electron microscopy (cryo-EM) and interpreted what they were doing. We then needed to see if the ...
Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published today in Nature Communications. The subtle changes might be enough to alter the binding ...