Fred Hutch researchers have done pioneering work in the areas of gene regulation, chromatin organization and cell cycle state, including quiescence. Gene expression is important because a specific ...

Researchers hope the AI tool will aid in the development of cell-specific gene therapies to treat diseases such as cancer.

On the other hand, when the tails of histone molecules are acetylated at specific locations, these molecules have less interaction with DNA, thereby leaving it more open. The regulation of the ...

EMBL researchers showed for the first time that adding a sugar to proteins inside cells is crucial for embryo development and for shutting down ...

A new technology, mvGPT, is capable of precisely editing genes, activating gene expression, and repressing genes all at the same time.

Enhancers controlling Drosophila coloration Until now, enhancers were thought to be modular. The term implies that each enhancer occupies an isolated stretch of DNA. "We have shown, however, that ...

DNA’s iconic double helix has long been the symbol of life’s blueprint. However, the human genome conceals far more ...

Penn researchers introduce mvGPT, a gene editing tool that edits DNA, activates genes and represses gene expression ...

Usher syndrome (USH) is a rare hereditary genetic disorder characterized by hearing loss, visual impairment, and balance dysfunction. Patients with USH have ...

If this regulation goes awry, it can lead to serious diseases such as cancer, inflammatory diseases, or neurodegeneration. Despite its importance, understanding gene regulation has been very ...