The sugar-phosphate backbone forms the structural framework of nucleic acids, including DNA and RNA. This backbone is composed of alternating sugar and phosphate groups, and defines directionality ...
plays a central role in DNA repair by cleaving the DNA backbone 5′ of AP sites that result from removal of damaged bases. New structural findings on APE1–DNA cocrystals provide insights into ...
Combinations of these atoms form the sugar-phosphate backbone of the DNA -- the sides of the ladder, in other words. Other combinations of the atoms form the four bases: thymine (T), adenine (A ...