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【Cell子刊】基因革命:北大魏文胜团队揭示DNA损伤修复新机制
【导读】保持基因组稳定性,对细胞平衡至关重要。在这项研究中,团队将CRISPR介导的碱基编辑与集合筛选技术相结合,确定了赖氨酸残基和蛋白质编码基因的大量突变。这些赖氨酸残基和基因的缺失,导致了对DNA损伤剂的敏感性或抗性。2024年12月10日,北京 ...
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