The mutations that cause Li-Fraumeni syndrome occur on the TP53 gene and CHEK2, which are both tumor suppressor genes. The average chance of a Li-Fraumeni syndrome patient to develop any form of ...

Specifically, they compared the gene burden for significantly mutated genes in each of the cohorts against all other cohorts combined. Compared to the other cohorts, RCC patients from Japan were ...

In 2015, Garton decided to undergo genetic testing to see if she or her daughters were at an increased risk of developing the ...