As shown on the right, TES release the interleukin IL-2, which stimulates CAR-T cells to multiply, and anti-CD3 and anti-CD28, two antibodies that, similar to tumor antigens presented by an ...
or CD3/CD28 magnetic beads, along with the addition of relevant growth factors to activate T cells. During this process, the CD28-mediated co-stimulatory signal plays a central role. Multiple studies ...