Researchers have uncovered an unexpected role for the molecule netrin1 in organizing the developing spinal cord.

The protein netrin1 has an entirely unanticipated role in organizing the spinal cord during early development.

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have uncovered an ...

A central question in adult stem cell biology is elucidating the signaling pathways regulating their dynamics and function in diverse physiological and age-related contexts. Muscle stem cells in ...

Additionally, the receptor-regulated Smad8 seems to represent the essential signalling molecule in tenocytes after BMP-7 stimulation. An important role of Smad8 in tenogenic differentiation was ...

The work is published in the journal Nature Communications. In the absence of BMP, the signaling molecule beta-catenin takes on the role of the Nodal antagonist. This new mechanism could be a flexible ...

The study demonstrates that activating the vitamin D receptor (VDR) with calcitriol suppresses cell proliferation in ...

Glypican members of the heparan sulphate proteoglycan family regulate several developmental signalling pathways, such as those involving Hedgehog, Wnt, BMP and FGF. Two studies reveal opposite ...