The protein netrin1 has an entirely unanticipated role in organizing the spinal cord during early development.

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have uncovered an ...

Researchers have uncovered an unexpected role for the molecule netrin1 in organizing the developing spinal cord.

The work is published in the journal Nature Communications. In the absence of BMP, the signaling molecule beta-catenin takes on the role of the Nodal antagonist. This new mechanism could be a flexible ...

Discussion The study showed that the type I receptor BMPR-Ib and the type II receptor BMPR-II seem to be the most regulated receptors on their mRNA level after tenocyte stimulation with BMP-7.

This work is an important contribution to understanding the role of FGF signaling in the induction of primitive-like cells in a 2D system of human gastrulation. The authors provide compelling evidence ...

Glypican members of the heparan sulphate proteoglycan family regulate several developmental signalling pathways, such as those involving Hedgehog, Wnt, BMP and FGF. Two studies reveal opposite ...