Researchers have identified a KIF18A gene variant that accelerates egg aging, increasing the risk of miscarriage and early infertility. The study highlights the causal relationship between the variant ...

In what could be a major advance in understanding the genetic causes underlying human infertility, scientists led by ...

A new study finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast cancer. The findings question ...

In the latest PNAS paper 2, aneuploidy as the functional genetic basis of cancer passes both these tests in ways that should be of interest to biotechnologists of a variety of stripes. Of all the ...

Most human pre-implantation are mosaics of euploid and aneuploid cells, however, mosaic embryos with a low proportion of aneuploid cells have a similar likelihood of developing to term as fully ...

Chromosomal abnormalities occur in 0.1% to 0.2% of live births, and the most common clinically significant aneuploidy among live-born infants is Down syndrome (trisomy 21). Other sonographically ...

Sameer Raniga, MD, DNB; P.D. Desai, MD; Hetal Parikh, MD The most commonly studied soft markers of aneuploidy include a thickened nuchal fold, rhizomelic limb shortening, mild fetal pyelectasis ...