Recent studies implicate the immune system and a herpes virus as potential contributors to development of disease ...

"The inherited form of Alzheimer's disease can be caused by mutations to the gene that encodes for the amyloid precursor protein," explains ... of the amyloid beta peptides into fibrillar ...

Lactylation is a reversible, covalent, post-translational modification of proteins. It occurs exclusively on lysine residues, where it influences protein structure, stability, localization, and ...

Nirmalraj and team clarify the shape and size of these protein clumps, but details of their structure are yet to be resolved. These details include if and how amyloid beta 42 differs chemically ...

The disease is linked to a build-up of the protein amyloid beta in the brain ... into the brain’s ‘glymphatic system’ — a structure discovered in 2013 that is similar to the body ...

In these pathological states, proteins like Tau, Amyloid beta, alpha-synuclein ... Successfully induced PFFs display a fibril structure under an electron microscope. The ThT assay, a classic ...