Amyl Therapeutics, headquartered in Liège, Belgium, is developing a novel anti-amyloid protein therapeutic that binds to a common structural feature of amyloids, the cross-β amyloid fold ...

Several mutations affecting β-amyloid, either to APP 1,2,3 ... including the hippocampus. LTP is a model of such use-dependent enhancement in synaptic efficacy, and can be induced by activating ...

Recent studies implicate the immune system and a herpes virus as potential contributors to development of disease ...

A study published in 2022 revealed a tenuous but plausible link between picking your nose and increasing the risk of ...

Recent advances in molecular biology have provided unprecedented insights into the structure of amyloid fibrils associated ...

Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that ...

elegans model that produces human beta-amyloid (amyloid-β 42), causing proteins to clump and form amyloid plaques, ...

Most treatments being pursued today to protect against Alzheimer’s disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research from Mass General Brigham and ...

Cutting-edge fluorescent cholesterol probes now enable scientists to visualize cholesterol movement and distribution in live ...

Amyloidosis develops from a bone marrow disorder. It occurs when an abnormal protein, called amyloid, builds up and forms deposits in the body. Amyloidosis is closely linked to MM. Amyloid light ...

This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...