The development of genetically modified adenovirus (Ad ... His tag to the fiber protein of an Ad5 vector specifically mediates cellular entry via an artificial receptor. Hence, by retaining ...

Adenoviral vectors will transduce a wide range of target cells resulting in high-level gene expression. They are non-integrating vectors so expression in dividing cells is progressively lost. First ...

Ad5 vectors are the most commonly used adenovirus vector. Ad5 vectors transduce a wide range of cell types. They utilize the Coxsackie-Adenovirus Receptor (CAR) to enter cells. Transduction efficiency ...