该研究表明，过量的F-肌动蛋白（F-actin）是大脑衰老的标志，会导致大脑衰老并限制健康寿命，而针对性地抑制F-肌动蛋白能够逆转大脑衰老表型并显著延长健康寿命。

Drosophila melanogaster, or fruit flies, are convenient research tools, and they have many genes in common with humans. | ...

The actin cytoskeleton provides force for dynamic cellular processes, such as motility, morphogenesis, cell division, endocytosis, and phagocytosis. The organization and dynamics of actin filaments ...

Actin, a family of proteins that help give cells their shape, are abundant throughout the body. F-actin forms filaments that ...

The actin filament exists as a structure of the fixed length and bears the muscle contraction and the adjustment on a muscular inside. The circulation and the molecule movements of the polymerization ...

The hope is that this discovery could further efforts to slow human aging and extend our lifespans. The main discovery relies ...

Research in the fruit fly Drosophila by scientists at the University of California, Los Angeles (UCLA) has now found that buildup of a common cell structural protein, filamentous actin (F-actin ...

In turn, the cytoskeleton relies on a type of actin protein, called filamentous or F-actin. It forms networks of thin, flexible filaments that affect the shape, stiffness, and movement of cells.

Buildup of a protein called filamentous actin, or F-actin, in the brain inhibits the removal of cellular wastes, including DNA, lipids, proteins and organelles. The resulting accumulation of waste ...