New treatment for advanced prostate cancer could be 'exciting step'
The drug, known as NXP800, works by targeting the heat shock factor 1 (HSF1) pathway, a cellular protective mechanism that is ...
Nature2 年
New studies shed light on breast cancer in young women
The results showed that younger women with breast cancer more frequently had mutations in two genes: GATA3 and ARID1A. Both of these genes play a role in tumour suppression, and mutations in them ...
MedPage Today13 天
In DLBCL, a Molecular Signature Predicts Primary Treatment Resistance
Key mutations were observed in TP53 and ARID1A genes and TP53 pathway was downregulated in patients with primary treatment resistance. A high-risk signature based on the identified molecular ...